Zoloft has been studied thoroughly in clinical trials, in which a group of people taking the drug have side effects documented and compared to another group not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
In these studies, the most common Zoloft side effects included:
- Nausea — in up to 30 percent of people
- Insomnia — up to 28 percent (see Zoloft and Insomnia)
- Ejaculation problems — up to 19 percent (see Zoloft Sexual Side Effects)
- Diarrhea or loose stools — up to 24 percent
- Dizziness — up to 17 percent
- Dry mouth — up to 16 percent (see Zoloft and Dry Mouth)
- Fatigue — up to 16 percent
- Drowsiness — up to 15 percent
- Indigestion — up to 13 percent
- Shakiness (tremor) — up to 11 percent
- Loss of appetite — up to 11 percent
- Decreased sex drive (libido) — up to 11 percent
Other common side effects that occurred in more than 2 percent of people included:
- Increased sweating
- Burning or tingling sensation (paresthesias)
- Pain
- Headache (see Zoloft and Migraines)
- Weight loss (see Zoloft and Weight Loss)
- Abdominal pain (stomach pain)
- Constipation
- Vision changes
- Hot flashes
- Nervousness
After being released in 1992, the makers of Zoloft have been involved in several zoloft lawsuits. One such lawsuit occurred in 1996 when Pfizer received a letter of warning from a subdivision of the FDA known as the Federal Division of Drug Marketing, Advertising, and Communications. This letter accused Pfizer of marketing and selling Zoloft outside of the FDA approved reasons for its use. This letter was made public so that anyone would have access to it. It is rare for warning letters such as this to be made public.

I thank you humbly for srahing your wisdom JJWY
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